2. Etiological Mechanism (Gene Abnormalities)

Cycle as the Etiological Mechanism of Tinnitus

Peripheral tinnitus is a good candidate for inclusion under the NO/ONOO – cycle etiological mechanism, fitting each of the five principles of this mechanism. Cases of tinnitus are initiated by at least 11 short-term stressors increasing nitric oxide or other cycle mechanisms. Such cycle elements as N -methylD -aspartate activity; oxidative stress; nitric oxide; peroxynitrite; vanilloid activity...

[Pathophysiology and gene abnormalities of endocrine tumors].

Various functioning and non-functioning tumors arise from endocrine glands in both the sporadic and familial forms and pathophysiology of the tumors is variable due to differences in the sort of tumor-bearing endocrine organs and in the amount of hormones released. In this paper, gene abnormalities in growth hormone (GH)-secreting pituitary adenoma, ectopic GHRH-producing tumor, multiple endocr...

Stillbirths and non-lethal abnormalities--a mechanism of death?

Pancytopenia: An Etiological Profile

Pancytopenia is the deficiency of all 3 cellular elements of blood, resulting in anemia, leucopenia, and thrombocytopenia. Pancytopenia may arise due to a number of disease processes that vary according to population, age, nutritional status, and the prevalence of infections [1]. Pancytopenia is a common hematological condition of varied etiology; however, only a few studies on pancytopenia fro...

Erectile Dysfunction Etiological Factors

Recent studies have demonstrated the association between ED and cardiovascular diseases Zambon, 2010; Bal, 2007. Ultrasensible C Reactive Protein (CRP) is an early marker of cardiovascular risk, and patients with ED have higher levels of CRP. Risk factors such as hypertension, smoking, obesity, diabetes mellitus, metabolic syndrome and sedentary lifestyle are pretty common in patients with coro...